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Mito-TEMPO

CAS No. : 1334850-99-5

MCE 国际站：Mito-TEMPO

产品活性：Mito-TEMPO 是一种靶向线粒体的超氧化物歧化酶模拟物，有着清除超氧化物和烷基自由基的能力。

研究领域：Metabolic Enzyme/Protease  |  NF-κB  |  Immunology/Inflammation

作用靶点：Mitochondrial Metabolism  |  Reactive Oxygen Species

In Vivo: Mito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3.

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货号: HY-112879

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