MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Fmoc-Thr[GalNAc(Ac)3-α-D]-OH

CAS No. : 116783-35-8

MCE 国际站：Fmoc-Thr[GalNAc(Ac)3-α-D]-OH

产品活性：Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 是用于研究制备癌症疫苗的结构单元。

研究领域：Others

作用靶点：Amino Acid Derivatives

In Vitro: The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn +antigen). This precursor is generated in the Golgi apparatus on newly synthesized glycoproteins by a family of polypeptide α- N-acetylgalactosaminyltransferases (ppGalNAcTs) and then extended to the common core 1 O-glycan Galβ1-3GalNAcα1-OSer/Thr (T antigen) by a single enzyme termed the T-synthase (core 1 β3-galactosyltransferase or C1GalT). Formation of the active form of the T-synthase requires a unique molecular chaperone termed Cosmc, encoded by Cosmc on the X-chromosome.

相关产品：Boc-D-Glu-OBzl  |  (4S)-1-Boc-4-fluoro-D-proline  |  (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid  |  (S)-2-(Benzylamino)-3-(4-hydroxyphenyl)propanoic acid  |  Dansylglycine  |  trans-N-Methyl-4-methoxyproline  |  Z-D-Glu(OtBu)-OH  |  H-D-Cys(Bzl)-OH  |  3-Bromo-L-phenylalanine  |  (S)-Methyl 2-amino-2-cyclopentylacetate hydrochloride  |  (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic acid  |  Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH  |  (S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate  |  Fmoc-Ser-OH  |  Boc-Ser(Me)-OH  |  Boc-Asp(OtBu)-OH  |  1,4,4-Trimethyl-L-proline  |  (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(allyloxy)-4-oxobutanoic acid  |  (S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoic acid  |  N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester  |  (2S)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-3-methylbutanoic acid  |  (R)-2-amino-3-cyclobutylpropanoic acid  |  S-(Acetamidomethyl)-L-cysteine hydrochloride  |  Fmoc-D-Ala-OH  |  L-Methionine methyl ester hydrochloride  |  H-Ser(Bzl)-OMe.HCl  |  Fmoc-Pra-OH  |  Fmoc-Asp(OtBu)-Osu  |  (±)-α-Methyl-(4-sulfonophenyl)glycine  |  Fmoc-D-Gly(allyl)-OH

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸  |  抗体  |  点击化学

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

货号: HY-P0232

品牌介绍:
•   MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；
•   50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
•   产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
•   提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；
•   专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。