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Flaconitine

CAS No. : 77181-26-1

MCE 国际站：Flaconitine

产品活性：Flaconitine 是一种生物碱。Flaconitine 是一种 NF-κB 抑制剂。

研究领域：NF-κB

作用靶点：NF-κB

结构分类：生物碱

来源：植物  |  其他科

In Vitro: Flaconitine has been demonstrated to suppress TNF-α induced NF-κB activation and is considered as a diester-diterpenoid-type NF-κB inhibitor Flaconitine (3-Acetylaconitine) is evaluated for its cytotoxic activity against human leukemic P388 cells using the SRB (Sulforhodamine B) method, with Etoposide as the positive control. The cell growth inhibitory potency of Flaconitine is expressed as IC₅₀ (μM) Value. Flaconitine exhibits moderately cytotoxic activity with an IC₅₀ of 18.6 μM.

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