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CAS No. : 141136-83-6
MCE 国际站:TRAP-6
产品活性:TRAP-6 (PAR-1 agonist peptide),一种多肽片段,是选择性的蛋白酶激活受体 1 (PAR1) 激动剂。TRAP-6 通过凝血酶受体激活人血小板。TRAP-6 对 PAR4 无活性。
研究领域:GPCR/G Protein
作用靶点:Protease Activated Receptor (PAR)
In Vitro: TRAP-6 (0.01-10 μM) triggers calcium mobilization in Xenopus oocytes heterologously expressing PAR1.
TRAP-6 (0.01-10 μM; 30 min) activates human platelets.
TRAP-6 (100 μM) does not cause the platelets of rabbits or rats to change shape, aggregate, release granule contents, or form thromboxane.
In Vivo: TRAP (1 mg/kg; i.v.) produces a biphasic response in blood pressure in inactin-anesthetized rats.
相关产品:Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | Peptidomimetic Library | Targeted Diversity Library | Peptide Library | Coagulation and Anti-coagulation Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Highly Selective Activators Library | Protease-Activated Receptor-3 (PAR-3) (1-6), human | I-191 | FSLLRY-NH2 TFA | VKGILS-NH2 | AC-55541 | FR-171113 | Protease-Activated Receptor-1 antagonist 3 | PAR-4 Agonist Peptide, amide TFA | Aeruginosin 98-B | AZ3451 | 2-Furoyl-LIGRLO-amide | AC-264613 | tcY-NH2 | ENMD-1068 hydrochloride | SLIGRL-NH2 | Protease-Activated Receptor-1, PAR-1 Agonist | CBK289001 | GB-110 hydrochloride | PAR-4 Agonist Peptide, amide | GB-88 | RWJ-56110 | Trypsin (MS grade) | AZ8838 | UDM-001651 | Parmodulin 2 | TFLLR-NH2 | Vorapaxar | SCH79797 dihydrochloride | TRAP-6-IN-1
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