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Hypericin

CAS No. : 548-04-9

MCE 国际站：Hypericin

产品活性：Hypericin 是一种天然存在于贯叶连翘中的物质。Hypericin 是 PKC (蛋白激酶C)、MAO (单胺氧化酶)、多巴胺-beta-羟化酶、逆转录酶、端粒酶和CYP (cytochrome P450) 的抑制剂。Hypericin 具有抗肿瘤、抗病毒和抗抑郁的活性，可诱导细胞凋亡。

研究领域：Apoptosis  |  Anti-infection  |  Neuronal Signaling  |  TGF-beta/Smad  |  Epigenetics  |  Metabolic Enzyme/Protease  |  Cell Cycle/DNA Damage

作用靶点：Apoptosis  |  Influenza Virus  |  Antibiotic  |  Monoamine Oxidase  |  PKC  |  Cytochrome P450  |  Dopamine β-hydroxylase  |  Reverse Transcriptase  |  Telomerase

结构分类：酚类  |  多酚类  |  其他类

来源：植物  |  藤黄科  |  贯叶连翘

In Vitro: Hypericin (0.25-4 μM; 24 h) inhibits the growth of fibroblasts (Fb), melanocytes (Mc), and keratinocytes (Kc).
Hypericin (3 μM; 24 h) treatment can induce cells apoptosis.

In Vivo: Hypericin (Intravenous injection; 10 mg/kg; once) treatment delays tumor growth.

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