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MCE 国际站:Annexin A2/ANXA2 Protein, Human
Annexin A2/ANXA2 Protein, Human是一种36-kDa的多功能蛋白,属于Annexin家族。Annexin A2在调节细胞生长和信号转导通路中起重要作用。Annexin A2也可作为一种自分泌因子,可以提高破骨细胞形成和骨吸收。
Synonyms: rHuAnnexin A2; ANXA2; Annexin A2
Species: Human
Source: E. coli
Biological Activity: Measured in a cell proliferation assay using A549 cells. The ED50 this effect is 0.7184 ng/mL, corresponding to a specific activity is 1.39×106 units/mg.
研究背景:The Annexins comprise a family of proteins that are involved in many aspects of cellular membrane dynamics and the regulation of membrane-associated proteins. Annexin A2 is an important member of annexin family of proteins expressed on surface of endothelial cells (ECs), macrophages, mononuclear cells and various types of cancer cells. Annexin A2 exhibits high affinity binding for calcium (Ca2+) and phospholipids. ANX A2 plays an important role in many biological processes such as endocytosis, exocytosis, autophagy, cell-cell communications and biochemical activation of plasminogen.
蛋白编号:P07355 (S2-D339)
基因 ID:302
产品分类:其他
Categories:Others
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