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MCE 国际站:Enterokinase Protein, Bovine (P.pastoris, His)
Enterokinase Protein, Bovine (P.pastoris, His)是在 P. pastoris 中产生的具有 His 标签的糖基化肽链。Enterokinase 起着将胰蛋白酶原转化为其活性形式胰蛋白酶的作用。
Synonyms: rBoEnterokinase, His; Enteropeptidase; ENTK; PRSS7
Species: Bovine
Source: P. pastoris
Biological Activity: 100 IU/μg Unit Definition: One unit is defined as the amount of enzyme needed to cleave 50 μg of fusion protein in 16 hours to 95% completion at 22°C in a buffer containing 25mM Tris-HCl, pH 8.0.
研究背景:Bovine enterokinase is a serine protease and functions as the physiological activator of trypsinogen. The amino acid composition shows that the light chain has nine half-cystine residues and that one half-cystine was in a disulfide link between the light and heavy subunits. The sequence has homologies with other serine proteases containing one or two chains. The homologies suggest that the catalytic subunit has the same three-dimensional structure and, therefore, the same mechanism of enzymatic action as pancreatic chymotrypsin, trypsin, and elastase. The presence of the conserved amino-terminal activation peptide sequence (IVGG) shows that enterokinase must have a zymogen precursor and that the two-chain enzyme arises from limited proteolysis during posttranslational processing.
蛋白编号:/
基因 ID:/
产品分类:酶和调节子 | 水解酶
Categories:Enzymes & Regulators | Hydrolases (EC 3)
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