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ICAM-2/CD102 Protein, Human (199a.a, HEK293, His)

MCE 国际站：ICAM-2/CD102 Protein, Human (199a.a, HEK293, His)

CD102 Protein, Human (HEK293, His)是免疫球蛋白超家族的跨膜糖蛋白。

Synonyms: rHuCD102, His; Intercellular Adhesion Molecule 2; ICAM-2; CD102; ICAM2

Species: Human

Source: HEK293

研究背景：ICAM-2 (CD102), like the structurally related ICAM-1 (CD54) and ICAM-3 (CD50) proteins is a known ligand for the ß2 family of leukocyte integrins. These include CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), and the dendritic cell-specific, ICAM-grabbing non-integrin (DC-SIGN) protein. ICAM-2 harbours two immunoglobulin domains which are homologues to the first and second immunoglobulin domain of ICAM-1 without any known splice variants. ICAM-2 is uniformly present on all subsets of B lymphocyte lineage cells in bone marrow cell suspensions. High level constitutive expression on vascular endothial cells and less responsiveness than ICAM-1 to inflammatory stimuli are also characteristics of ICAM-2. Recombinant ICAM-2 can co-stimulate T cells in vitro. Although ICAM-2 mediates neutrophil transmigration, ICAM-2 appears capable of mediating CD31/PECAM-1-independent leukocyte transmigration. ICAM-2 may also regulate angiogenesis via several mechanisms including survival, cell migration, and Rac activation.

蛋白编号：P13598 (K25-Q223)

基因 ID：3384

产品分类：受体蛋白  |  细胞粘附分子  |  免疫球蛋白超家族细胞粘附分子  |  ICAM-2/CD102  |  CD 抗原  |  NK 细胞 CD 蛋白  |  ICAM-2/CD102  |  CD 抗原  |  巨噬细胞 CD 蛋白  |  ICAM-2/CD102  |  CD 抗原  |  单核细胞 CD 蛋白  |  ICAM-2/CD102  |  CD 抗原  |  血小板 CD 蛋白  |  ICAM-2/CD102  |  CD 抗原  |  红细胞 CD 蛋白  |  ICAM-2/CD102  |  CD 抗原  |  树突细胞 CD 蛋白  |  ICAM-2/CD102  |  CD 抗原  |  内皮细胞 CD 蛋白  |  ICAM-2/CD102

Categories：Receptor Proteins  |  Cell Adhesion Molecules (CAMs)  |  Immunoglobulin-like Cell Adhesion Molecules  |  ICAM-2/CD102  |  CD Antigens  |  NK Cell CD Proteins  |  ICAM-2/CD102  |  CD Antigens  |  Macrophage CD Proteins  |  ICAM-2/CD102  |  CD Antigens  |  Monocyte CD Proteins  |  ICAM-2/CD102  |  CD Antigens  |  Platelet CD Proteins  |  ICAM-2/CD102  |  CD Antigens  |  Erythrocyte CD Proteins  |  ICAM-2/CD102  |  CD Antigens  |  Dendritic Cell CD Proteins  |  ICAM-2/CD102  |  CD Antigens  |  Endothelial cell CD Proteins  |  ICAM-2/CD102

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