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MCE 国际站:Nectin-2/CD112 Protein, Human (HEK293, His)
CD112 Protein, Human (HEK293, His)是一种在 HEK 293 细胞中表达的,N 末端有 His 标签的重组人 CD112。CD112 Protein 可用作人 DNAM-1 (CD226) 激活分子的细胞表面配体。
Synonyms: rHuCD112, His; Poliovirus Receptor-Related Protein 2; Herpes Virus Entry Mediator B; Herpesvirus Entry Mediator B; CD112; PVRL2; HVEB; PRR2
Species: Human
Source: HEK293
Biological Activity: Immobilized Human DNAM-1-Fc at 2μg/ml (100 μl/well) can bind recombinant Human CD112, His (HEK293-expressed) (rHuCD112, His). The ED50 of recombinant Human CD112, His (HEK293-expressed) (rHuCD112, His) is 0.3-1.5 μg/mL.
研究背景:Nectin-2 (CD112) is a 60 (Nectin-2 α) or 65 kDa (Nectin-2 δ) type I TM glycoprotein that expressed in a variety of cells. Nectin is a Ca2+-independent immunoglobulin-like intercellular adhesion molecule. Nectin comprises a family of at least four members nectin-1, nectin-2, nectin-3 and nectin-4. All the members have two or three splice variants (except nectin-4), and have an extracellular region containing three Ig-like domains, a single transmembrane region and a cytoplasmic region (except nectin-1γ). Nectin-1, nectin-2 and nectin-3 are ubiquitously expressed in a variety of cells. Nectin-2 and nectin-3 are also expressed in cells that lack cadherins. Human nectin-4 is expressed mainly in the placenta.
蛋白编号:Q92692-2 (Q32-L360)
基因 ID:5819
产品分类:受体蛋白 | 细胞粘附分子 | 免疫球蛋白超家族细胞粘附分子 | Nectin-2/CD112 | CD 抗原 | NK 细胞 CD 蛋白 | Nectin-2/CD112 | CD 抗原 | 巨噬细胞 CD 蛋白 | Nectin-2/CD112 | CD 抗原 | 干细胞 CD 蛋白 | Nectin-2/CD112 | CD 抗原 | 血小板 CD 蛋白 | Nectin-2/CD112 | CD 抗原 | 上皮细胞 CD 蛋白 | Nectin-2/CD112 | CD 抗原 | 内皮细胞 CD 蛋白 | Nectin-2/CD112 | 免疫检查点蛋白 | 抑制性免疫检查点 | 免疫检查点蛋白 | 刺激性免疫检查点
Categories:Receptor Proteins | Cell Adhesion Molecules (CAMs) | Immunoglobulin-like Cell Adhesion Molecules | Nectin-2/CD112 | CD Antigens | NK Cell CD Proteins | Nectin-2/CD112 | CD Antigens | Macrophage CD Proteins | Nectin-2/CD112 | CD Antigens | Stem Cell CD Proteins | Nectin-2/CD112 | CD Antigens | Platelet CD Proteins | Nectin-2/CD112 | CD Antigens | Epithelial cell CD Proteins | Nectin-2/CD112 | CD Antigens | Endothelial cell CD Proteins | Nectin-2/CD112 | Immune Checkpoint Proteins | Inhibitory Checkpoint Molecules | Immune Checkpoint Proteins | Stimulatory Immune Checkpoint Molecules
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