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MCE 国际站:SCF Protein, Mouse (P.pastoris)
SCF Protein, Mouse (P.pastoris)是受体型蛋白酪氨酸激酶 KIT 的配体。在调节细胞存活和增殖,造血,干细胞维持,配子发生,肥大细胞发育,迁移和功能以及黑素生成中起重要作用。
Synonyms: rMuSCF; Hematopoietic growth factor KL; MGF; Mast Cell Growth Factor
Species: Mouse
Source: P. pastoris
Biological Activity: The ED50 is <10.0 ng/mL as measured by human TF-1 cells, corresponding to a specific activity of >1.0× 105 units/mg.
研究背景:Embryo implantation is a complex process that requires the interaction of embryo and endometrium. Several growth factors and cytokines appear to be involved in this process. Stem cell factor (SCF) and its receptor c-kit regulate the proliferation and survival of germ cells and play an important role in follicular development. During embryonic development, SCF and c-kit are essential for the survival and proliferation of the germ cell and migration toward the gonad. c-kit mRNA is expressed in the primordial germ cells, while the SCF transcript is expressed along their migratory pathway toward the genital ridge.
蛋白编号:P20826 (K26-A189)
基因 ID:17311
产品分类:细胞因子和生长因子
Categories:Cytokines and Growth Factors
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