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IL-2 Protein, Mouse

MCE 国际站：IL-2 Protein, Mouse

IL-2 Protein, Mouse是一种免疫调节细胞因子，具有广泛的功能，包括促进细胞凋亡，增殖和淋巴细胞的存活。

Synonyms: rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

Species: Mouse

Source: E. coli

Biological Activity: Measured by a cytotoxicity assay using CTLL-2 Cells. The ED₅₀ this effect is ≤ 0.5117 ng/mL, corresponding to a specific activity is ≥ 1.954×10⁶ units/mg.

研究背景：Interleukin-2 (IL-2) is a multi-faceted cytokine, known for promoting proliferation, survival, and cell death depending on the cell type and state. For example, IL-2 facilitates cell death only in activated T cells when antigen and IL-2 are abundant. The availability of IL-2 clearly impacts this process. IL-2 is retained in blood vessels by heparan sulfate, and that biologically active IL-2 is released from vessel tissue by heparanase. The morphologic changes and rapid cell death induced by dimeric IL-2 imply that cell death is mediated by disruption of membrane permeability and subsequent necrosis. IL-2 has a direct and unexpectedly broad influence on cellular homeostatic mechanisms in both immune and non-immune systems.

蛋白编号：P04351 (A21-Q169)

基因 ID：16183

产品分类：细胞因子和生长因子  |  白细胞介素  |  白细胞介素-2

Categories：Cytokines and Growth Factors  |  Interleukin & Receptors  |  IL-2

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