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Estradiol benzoate
CAS No. : 50-50-0
MCE 国际站:Estradiol benzoate
产品活性:Estradiol benzoate (β-Estradiol 3-benzoate) 是一种 HBx蛋白 的抑制剂,抑制雄激素和乙型肝炎病毒(HBV) 的转录,复制。Estradiol benzoate 具有抗生育作用和抗弓形虫活性并且能够改善 Ovx 雌性小鼠的记忆行为。
研究领域:Vitamin D Related/Nuclear Receptor | Anti-infection | Apoptosis
作用靶点:Estrogen Receptor/ERR | HBV | Bcl-2 Family
In Vitro: Estradiol benzoate (5-75 μM, 24 h-48 h) has a downregulation effect on HBV translation, transcription, and replication in SBHX21 cells.
Estradiol benzoate (0-500 μM, 72 h) has toxicity to Human foreskin fibroblasts (HFFs).
In Vivo: Estradiol benzoate (20-100 μg/kg, Subcutaneous injection, once a day for 4-5 weeks) improves learning and memory behavior of Ovx female mice.
Estradiol benzoate (0.015-15000 μg/kg, Subcutaneous injection, single dose) advances male puberty in male Sprague-Dawley (SD) rats.
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