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Glucosamine
CAS No. : 3416-24-8
MCE 国际站:Glucosamine
产品活性:Glucosamine (D-Glucosamine) 是一种氨基糖, 是糖基化蛋白和脂质生化合成的突出前体, 用作膳食补充剂。Glucosamine 也是软骨基质和滑液中糖胺聚糖的天然成分,当外用时,对骨关节炎软骨和软骨细胞具有药理作用。
研究领域:Metabolic Enzyme/Protease | NF-κB | Immunology/Inflammation | Autophagy
作用靶点:Endogenous Metabolite | Reactive Oxygen Species | HIF/HIF Prolyl-Hydroxylase | Autophagy
In Vitro: Glucosamine (D-Glucosamine) exhibits dose-dependent DPPH antioxidant activity.
Glucosamine treatment of Short-term (4 h) inhibits HIF-1α at the protein level, decreases phosphorylation of p70S6K and S6, translation-related proteins.
Glucosamine significantly decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin in the obstructed kidneys and TGF-β1-treated renal cells.
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