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Aripiprazole

CAS No. : 129722-12-9

MCE 国际站：Aripiprazole

产品活性：Aripiprazole (OPC-14597) 是一种非典型抗精神病药，是一种有效、高亲和力的多巴胺 D2 受体部分激动剂。Aripiprazole 在 5-HT2B 和 5-HT2A 受体上是一种反向激动剂，并在 5-HT1A、5-HT2C、D3 和 D4 受体上显示部分激动剂作用。Aripiprazole 可用于精神分裂症和 COVID19 的研究。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：5-HT Receptor  |  Dopamine Receptor

In Vitro: Aripiprazole potently activates D2 receptor-mediated inhibition of cAMP accumulation.
Aripiprazole shows a greater anti-inflammatory effect on TNF-α, IL-13, IL-17α and fractalkine.

In Vivo: Aripiprazole (0-3 mg/kg, IP, daily) shows some anxiolytic properties.

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