耗材描述

NDI-091143 是一种有效的高亲和力人 ATP 柠檬酸裂解酶 (ACLY) 抑制剂，IC50 为 2.1 nM (ADP-Glo分析)，Ki 为 7.0 nM，Kd 为 2.2 nM。NDI-091143 通过稳定柠檬酸盐域中的大构象变化来间接抑制柠檬酸的结合和识别，从而抑制了 ACLY 催化变构反应。更多产品详情查看：www.medchemexpress.cn/ndi-091143.html

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