MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
SGC-CK2-1
CAS No. : 2470424-39-4
MCE 国际站:SGC-CK2-1
产品活性:SGC-CK2-1 是一种高效、ATP 竞争性的 CK2 化学探针,对两种人 CK2 亚型 CK2α 和 CK2α' 具有选择性,IC50分别为 36 和 16 nM。SGC-CK2-1 可用于神经退行性疾病的研究。
研究领域:Cell Cycle/DNA Damage | Stem Cell/Wnt
作用靶点:Casein Kinase
In Vitro: SGC-CK2-1 inhibits CSNK2A2 and CSNK2A1 with IC50s value of 2.3 and 4.2 nM.
SGC-CK2-1 inhibits DYRK2 with the IC50 value of 3.7 μM.
SGC-CK2-1 inhibits blood U-937, MV4-11, MOLM-13, OCI-LY19, OCI-AML5 cells with IC50s of 120, 690, 750, 760 and 810 nM, respectively. SGC-CK2-1 inhibits Head/Neck Detroit562 cells with an IC50 of 550 nM. SGC-CK2-1 inhibits Lung NCI-H2286 cells with an IC50 of 550 nM. SGC-CK2-1 inhibits Brain SK-N-MC cells with an IC50 of 730 nM. SGC-CK2-1 inhibits Breast BT-20 cells with an IC50 of 810 nM. SGC-CK2-1 inhibits Skin A375 cells with an IC50 of 830 nM. SGC-CK2-1 inhibits Stomach SNU-1 cells with an IC50 of 860 nM. SGC-CK2-1 inhibits Duodenum Hutu 80 cells with an IC50 of 920 nM.
相关产品:Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Kinase Inhibitor Library | Stem Cell Signaling Compound Library | Wnt/Hedgehog/Notch Compound Library | Anti-Aging Compound Library | Neurodegenerative Disease-related Compound Library | Cancer Stem Cells Compound Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Highly Selective Inhibitors Library | Serine/Threonine Kinase Inhibitor Library | Multi-Target Compound Library | LY294002 | Silmitasertib | IWP-2 | Emodin | Ellagic acid | D4476 | PF-670462 dihydrochloride | Umbralisib | TBB | TMX-4116 | Casein Kinase inhibitor A51 | DMAT | PF-4800567 | SR-3029 | (E/Z)-GO289 | FPFT-2216 | SSTC3 | IC261 | TAK-715 | CKI-7 free base | TTP 22 | BioE-1115 | CK1-IN-1 | AMG-548 dihydrochloride | BTX161 | PF-5006739 | TA-01 | CK2/ERK8-IN-1 | Hematein
热门产品线:重组蛋白 | 药物筛选 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
品牌介绍:
• MCE (MedChemExpress) 拥有200 多种全球独家化合物库,我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物;
• 50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域;
• 产品种类涵盖各种重组蛋白,多肽,常用试剂盒 ,更有 PROTAC、ADC 等特色产品,广泛应用于新药研发、生命科学等科研项目;
• 提供虚拟筛选,离子通道筛选,代谢组学分析检测分析,药物筛选等专业技术服务;
• 设有专业的实验中心和严格的质控、验证体系;
• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;
• 产品的生物活性多经各国客户实验验证;
• Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;
• 专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;
• 与世界各大制药公司及知名科研机构建立了长期的合作。