耗材描述
Oxindole
产品活性:Oxindole (Indolin-2-one) 是芳族杂环砌块。 Oxindole衍生物已成为激酶抑制剂研究中的主要化合物。
产品来源: https://www.medchemexpress.cn/NSC_274863.html
研究领域:Anti-infection | Metabolic Enzyme/Protease
作用靶点:HIV | Endogenous Metabolite
来源:植物 | 其他科
结构分类:生物碱 | 吲哚类生物碱 | 结构分类
In Vitro: Oxindole (Indolin-2-one) is a bicyclic structure consisting of a benzene ring fused to 2-pyrrolidone. Substituted indolinones can be referred as ‘privileged structures’ owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold. Oxindole has been found in tissues and fluids of mammals as well as natural products produced by a range of plants, bacteria and invertebrates. 2-indolinone derivatives possess diverse range of pharmacological activities including anti-cancer, anti-HIV, anti-diabetic, antibacterial, antioxidant, kinase inhibitory, AChE inhibitory, anti-leishmanial, b3 adrenergic receptor agonistic, phosphatase inhibitory, analgesic, spermicidal, vasopressin antagonists, progesterone antagonists, neuroprotection, NMDA blocker and sleep inducing activities.
相关产品:Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | Natural Product Library | Anti-Cancer Compound Library | Antiviral Compound Library | Human Endogenous Metabolite Compound Library | Fragment Library | Anti-diabetic Compound Library | Endocrinology Compound Library | Traditional Chinese Medicine Active Compound Library | Neuroprotective Compound Library | Alkaloids Library | Gut Microbial Metabolite Library | Anti-Cancer Natural Product Library | Antiviral Traditional Chinese Medicine Active Compound Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Human Metabolite Library | Animal-Sourced Natural Product Library | Bioactive Compound Library Max | Rapamycin | 3-Methyladenine | Chloroquine | Doxorubicin hydrochloride | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | Hydrocortisone | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Palmitic acid | Docetaxel | Isoprenaline hydrochloride | L-Ascorbic acid | Cytarabine | Q-VD-OPh | Melatonin | Calcitriol | Capsaicin | Arachidonic acid | Valproic acid | Oleic acid | β-Nicotinamide mononucleotide | Acetaminophen | Biotin | Corticosterone | Lactate
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