Seselin 产品活性：Seselin 是一种抗癌、抗炎、抗真菌剂，具有口服活性。 产品来源： https://www.medchemexpress.cn/seselin.html 研究领域：Anti-infection 作用靶点：Fungal 来源：植物 | 桑科 | 天仙果 结构分类：黄酮类 | 其他黄酮类 | 结构分类 In Vitro: Seselin shows cytotoxic effects with ED50 of 8.66 and 9.94 μg/mL against P-388 and HT-29 cells, respectively. Seselin (5-20 μM; 0.5-24 h) inhibits cytokine output from macrophages stimulated by LPS and IFN-γ dose- and time-dependently. Seselin (5-20 μM; 12 h) inhibits the expression of proinflammatory macrophage markers (iNOS, phagocytosis, CD11c) in BMDMs. Seselin (5-20 μM; 0.5-6 h) blocks the STAT1 signalling pathway. In Vivo: Seselin (0.5-40.5 mg/kg; s.c.; once) shows peripheral anti-inflammatory and antinociceptive activities in mice. Seselin (3-30 mg/kg; i.g.; once) ameliorates sepsis induced by caecal ligation and puncture in mice. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Immunology/Inflammation Compound Library | Natural Product Library | Anti-Cancer Compound Library | Antifungal Compound Library | Orally Active Compound Library | Flavonoids Library | Anti-Cancer Natural Product Library | Plant-Sourced Natural Product Library | Bioactive Compound Library Max | Rapamycin | Ferrostatin-1 | Cycloheximide | Staurosporine | Hygromycin B | Resveratrol | Tunicamycin | Oligomycin | Camptothecin | Filipin complex | Amphotericin B | Calcimycin | Monensin sodium | Nystatin | Ketoconazole | Itraconazole | Fluconazole | Valinomycin | Tofacitinib citrate | Caspofungin diacetate | Mycophenolic acid | Leptomycin B | Idarubicin hydrochloride | Toyocamycin | Terbinafine | Hyperoside | Saponins | Sinefungin | Carvacrol 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。