D-erythro-Sphingosine hydrochloride 产品活性：D-erythro-Sphingosine (Erythrosphingosine) hydrochloride 是一种特异性 TRPM3 活化剂。D-erythro-Sphingosine 还诱导视网膜母细胞瘤蛋白 (retinoblastoma protein) 去磷酸化。 产品来源： https://www.medchemexpress.cn/d-erythro-sphingosine-hydrochloride.html 研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling 作用靶点：TRP Channel In Vitro: Extracellular application of D-erythro-Sphingosine (20 μM) induces an increase in [Ca2+]i in TRPM3-transfected HEK293 cells within 20 to 30 s after start of application, whereas nontransfected control cells (NT) shows only very small responses. D-erythro-Sphingosine (10 μM) induces currents through TRPM3. Induction of retinoblastoma protein dephosphorylation by D-erythro-Sphingosine (500 nM; 24 h) precede inhibition of growth and a specific arrest in the G0/G1 phase of the cell cycle. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Membrane Transporter/Ion Channel Compound Library | Neuronal Signaling Compound Library | Natural Product Library | Mechanoreceptors Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Animal-Sourced Natural Product Library | Highly Selective Activators Library | Ion Channel Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | Rosiglitazone | GsMTx4 | Capsaicin | EIPA | Probenecid | 2-Aminoethyl diphenylborinate | Diphenyleneiodonium chloride | Amiloride hydrochloride | GSK1016790A | Capsazepine | HC-067047 | HC-030031 | ML-SA1 | GSK2193874 | Resiniferatoxin | Adenosine 5′-diphosphoribose sodium | AMG9810 | ML-SA5 | Caffeic acid | SKF-96365 hydrochloride | GSK205 | BI-749327 | (-)-Menthol | ML-SI1 | Pregnenolone | Anandamide | Pico145 | Pyr3 | (1R,2R)-ML-SI3 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。