耗材描述
1-Octanol
产品活性:1-Octanol (Octanol) 是一种饱和脂肪醇,是一种 T 型钙通道 (T-channels) 抑制剂,对天然 T 电流的 IC50 为 4 μM。1-Octanol 是一种具有柴油般特性的极具吸引力的生物燃料。
产品来源: https://www.medchemexpress.cn/1-octanol.html
研究领域:Neuronal Signaling | Membrane Transporter/Ion Channel | Metabolic Enzyme/Protease
作用靶点:Calcium Channel | Endogenous Metabolite
结构分类:其他类 | 结构分类
In Vitro: 1-octanol inhibits native T-currents at subanesthetic concentrations with an IC50 of approximately 4 μM. In contrast, 1-octanol is up to 30-fold less potent in inhibiting recombinant CaV3.3 T-channels heterologously expressed in human embryonic kidney cells.
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