耗材描述
Desaminotyrosine
产品活性:Desaminotyrosine 是一种微生物相关的代谢物,通过扩大 I 型干扰素 (type I interferon) 信号来阻止 influenza 的发生。
产品来源: https://www.medchemexpress.cn/Desaminotyrosine.html
研究领域:Anti-infection | Metabolic Enzyme/Protease
作用靶点:Influenza Virus | Endogenous Metabolite
结构分类:酚类 | 单酚类 | 酮、醛、酸
In Vivo: Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice.
相关产品:Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Metabolism/Protease Compound Library | Natural Product Library | Antiviral Compound Library | Human Endogenous Metabolite Compound Library | Fragment Library | Medicine Food Homology Compound Library | Phenols Library | Traditional Chinese Medicine Active Compound Library | Gut Microbial Metabolite Library | Microbial Metabolite Library | Food-Sourced Compound Library | Antiviral Traditional Chinese Medicine Active Compound Library | Human Metabolite Library | Animal-Sourced Natural Product Library | Multi-Target Compound Library | Bioactive Compound Library Max | Rapamycin | 3-Methyladenine | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | Hydrocortisone | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Palmitic acid | Docetaxel | Isoprenaline hydrochloride | L-Ascorbic acid | Tunicamycin | Cytarabine | Curcumin | Melatonin | Calcitriol | Capsaicin | Arachidonic acid | Valproic acid | U0126-EtOH | Oleic acid | Camptothecin | β-Nicotinamide mononucleotide | Acetaminophen | Biotin | Corticosterone
品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物,我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物;10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域;设有专业的实验中心和严格的质控、验证体系;提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;产品的生物活性多经各国客户实验验证;Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;与世界各大制药公司及知名科研机构建立了长期的合作。