Tetrac 产品活性：Tetrac (Tetraiodothyroacetic acid)，L-甲状腺素 (T4) 的天然衍生物，是甲状腺素整合素受体拮抗剂。Tetrac 阻断 T4 和 3,5,3'-triiodo-L-thyronine (T3) 在整联蛋白 αvβ3 上甲状腺激素的细胞表面受体处的作用。Tetra 具有抗血管生成和抗肿瘤活性。 产品来源： https://www.medchemexpress.cn/tetrac.html 研究领域：Cytoskeleton | Metabolic Enzyme/Protease 作用靶点：Integrin | Endogenous Metabolite 结构分类：酚类 | 单酚类 | 酮、醛、酸 In Vitro: Tetrac (0.01-1 μM; 2-6 d) induces anti-proliferation in HT-29 and HCT116 cells with different K-RAS status. Tetrac (0.1 μM; 30 min) inhibits activation of ERK1/2 in HT-29 and HCT116 cells. Tetrac (0.1 μM; 24 h) inhibits expression of CCND1 and c-Myc, but promotes expression of CASP2 and THBS1. In Vivo: Tetrac (35 μg; p.o. for 40 days) inhibits tumor inoculation, growth and integrin expression in mice. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | Metabolism/Protease Compound Library | Natural Product Library | Anti-Cancer Compound Library | Phenols Library | Cytoskeleton Compound Library | Orally Active Compound Library | Rare Diseases Drug Library | Anti-Cancer Natural Product Library | Human Metabolite Library | Membrane Protein-targeted Compound Library | Mitochondrial Toxicity Compound Library | Extracellular Vesicles (EVs) Compound Library | Bioactive Compound Library Max | Rapamycin | 3-Methyladenine | Acetylcysteine | 5-Fluorouracil | ATP | Retinoic acid | Hydrocortisone | Estradiol | Nicotinamide | Prostaglandin E2 | AICAR | Palmitic acid | Docetaxel | Isoprenaline hydrochloride | L-Ascorbic acid | Cytarabine | Melatonin | Calcitriol | Capsaicin | Arachidonic acid | Valproic acid | Oleic acid | β-Nicotinamide mononucleotide | Acetaminophen | Biotin | Corticosterone | Lactate | Cholesterol | NAD+ | DHEA 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。