耗材描述
Tremelimumab
产品活性:Tremelimumab (Ticilimumab) 是一种完全人源的单克隆抗体,对细胞毒性 T 淋巴细胞抗原 4 (CTLA-4) 具有特异性,可用于转移性黑色素瘤研究。
产品来源: https://www.medchemexpress.cn/tremelimumab.html
研究领域:Immunology/Inflammation
作用靶点:CTLA-4
In Vitro: Tremelimumab (Ticilimumab) has a higher affinity for CTLA-4-Ig than for CD28-Ig and that the antibody is specific for cynomolgus monkeys and humans.
Tremelimumab does not bind to human leukocyte FcγR and does not trigger the release of cytokines avoiding the cytokine release syndrome, but increases the IL-2 production upon stimulation with the staphylococcal enterotoxin A in a concentration-dependent manner.
Tremelimumab enhances the IL-2 production in T-cells.
相关产品:Ipilimumab | Abatacept | Anti-Mouse CTLA-4 Antibody (9D9) | Botensilimab | Vudalimab | Gotistobart | Nurulimab | Davoceticept | Firastotug | Lorigerlimab | Muzastotug | Quavonlimab | Sovipostobart | Tuvonralimab | Zalifrelimab
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