耗材描述
Substance P (6-11)
产品活性:Substance P (6-11) 是 Substance P (Substance P (HY-P0201)) 的 C 末端六肽酰胺。Substance P (6-11) 与 NK-1 速激肽受体结合。Substance P (6-11) 显示运动神经元的去极化和降压作用。
产品来源: https://www.medchemexpress.cn/substance-p-6-11.html
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Neurokinin Receptor
In Vitro: Substance P(6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation with an EC50 value 4 nM in rat urinary bladder.
In Vivo: Substance P (6-11) (0.1-10 nM) inhibits insulin and glucagon secretion from the rat pancreas in a dose-dependent manner. In the canine pancreas, by contrast, Substance P (6-11) (1-10 nM), potentiates the release of insulin, glucagon, and somatostatin.
相关产品:Substance P | Aprepitant | Fezolinetant | Senktide | Fosaprepitant dimeglumine | Netupitant | SB-222200 | Rolapitant | Saredutant | Talnetant | Maropitant | Casopitant mesylate | L-732138 | Elinzanetant | H-Glu(OtBu)-OtBu hydrochloride | Neurokinin A TFA | Vofopitant dihydrochloride | Osanetant | Neurokinin B TFA | Pavinetant | Substance P(1-7) TFA | Hemokinin 1, human | Orvepitant maleate | Hemokinin 1 (mouse) | Men 10376 TFA | Neurokinin A(4-10) TFA | NKP608 | Vapreotide
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