耗材描述
DALDA acetate
产品活性:DALDA acetate 是一种强效和高选择性 μ-opioid receptor 激动剂,其 Ki 为 1.69 nM。DALDA acetate 具有抗痛和呼吸作用。
产品来源: https://www.medchemexpress.cn/dalda-acetate.html
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Opioid Receptor
In Vitro: DALDA acetate carrys a net positive charge (3+) at physiological pH and is thus hydrophilic and more polar than morphine.
In Vivo: DALDA acetate (0-7 nmol/rat; i.t.; once) shows antinociceptive and respiratory effects in rats.
DALDA acetate (0.1 and 1.0 μg/side; ICV; once) results in biphasic effects, with an initial suppression, an intermediate marked inhibition, followed by activation for horizontal movement, rearing and stereotypy times in rats.
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