a-Helical Corticotropin Releasing Factor (12-41) 产品活性：a-Helical Corticotropin Releasing Factor (12-41) 是一种 30 个氨基酸长度的，促肾上腺皮质激素释放因子/激素的 α 螺旋类似物。促肾上腺皮质激素释放因子 (CRF) 是一种下丘脑激素，能刺激肾上腺皮质激素 (ACTH) 的分泌。a-Helical Corticotropin Releasing Factor (12-41) 则会抑制这种刺激作用。 产品来源： https://www.medchemexpress.cn/a-helical-corticotropin-releasing-factor-12-41.html 研究领域：GPCR/G Protein 作用靶点：CRFR In Vitro: a-Helical Corticotropin Releasing Factor (0.3 nM; 5-min pulses every 40 min alternately) shows the inhibitory effect on stimulated release of immunoreactive ACTH from perifused equine anterior pituitary cells in vitro.. a-Helical Corticotropin Releasing Factor (0.5-5 μM) suppresses CRH-induced ACTH secretion. In Vivo: a-Helical Corticotropin Releasing Factor (12-41) (15-150 μg; s.c.; isolated for 30 or 60 min) suppresses the active behavioral response characteristic of guinea pig pups to brief isolation in novel surroundings. 相关产品：Antalarmin hydrochloride | R121919 | Verucerfont | CRF, bovine TFA | Antisauvagine-30 TFA | Cortagine | NBI-27914 | Urocortin III, mouse TFA | Urocortin, human | CP 376395 | DMP 696 | Pexacerfont | Stressin I TFA | Tildacerfont | α-Helical CRF(9-41) | Urocortin, rat | [DPro5] Corticotropin Releasing Factor, human, rat TFA | Emicerfont | NVS-CRF38 | Sauvagine TFA | Urotensin I | (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) | (Tyr0)-Urocortin, rat | a-Helical Corticotropin Releasing Factor (9-41) 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。