耗材描述
Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
产品活性:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 是一种促黑素,一种刺激黑素细胞的激素。Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 能够刺激酪氨酸酶活性并在大鼠模型中表现出体温调节作用。
产品来源: https://www.medchemexpress.cn/ac-nle4-d-phe7-α-msh-4-10-nh2.html
研究领域:Metabolic Enzyme/Protease
作用靶点:Tyrosinase
In Vitro: Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 (0.1 pM-1 μM; 48 h) stimulates tyrosinase activity in a dose-dependent manner in Cloudman S91 mouse melanoma cells.
In Vivo: Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2 (0-50 pM; i.c.v.; single dose) exerts thermoregulatory effect in rats model.
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