Ecnoglutide 产品活性：Ecnoglutide (XW003) 是一种长效的 cAMP-biased 胰高血糖素样肽 1 (GLP-1) 受体激动剂。Ecnoglutide 可用于二型糖尿病和肥胖的研究。 产品来源： https://www.medchemexpress.cn/ecnoglutide.html 研究领域：GPCR/G Protein 作用靶点：GCGR In Vitro: Ecnoglutide induces cAMP but not GLP-1 receptor internalization (EC50 = 0.018 nM). In Vivo: Ecnoglutide (0.015, 0.15 mg/kg, s.c., a single time) reduces blood glucose, promotes insulin induction, and leads to more pronounced body weight reduction compared to Semaglutide (HY-114118) in db/db mice. Ecnoglutide (1 mg/kg, s.c., rats) shows the T1/2 (h), Tmax (h), Cmax (nM), AUClast (h*nM), MRT (h) values of 11.7, 18 .0, 387.3, 16274.8, 25.4 respectively. 相关产品：Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Peptide Library | Semaglutide | Exendin-4 | Liraglutide | Glucagon (1-29), bovine, human | Exendin(9-39) amide | Retatrutide | Orforglipron | GLP-1(7-37) | GLP-1(7-36), amide acetate | MK 0893 | Adomeglivant | BETP | Cotadutide acetate | GLP-1R Antagonist 1 | Danuglipron | GLP-1(9-36)amide | GLP-2(1-33)(human) | Oxyntomodulin (bovine, porcine) | Lixisenatide | Beinaglutide | Lotiglipron | Survodutide | NNC-0640 | Mazdutide | GLP-1R agonist 2 | LGD-6972 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。