耗材描述
[D-Asp3]-Microcystin-LR
产品活性:Microcystin-[D-Asp3]-LR/Microcystin A 是一种蓝藻毒素。Microcystin-[D-Asp3]-LR/Microcystin A 能够激活 Nrf2,促进氧化应激反应。Microcystin-[D-Asp3]-LR/Microcystin A 还可用于毒理学研究。
产品来源: https://www.medchemexpress.cn/d-asp3-microcystin-lr.html
研究领域:NF-κB
作用靶点:Keap1-Nrf2
In Vitro: Microcystin exhibits toxicity targeting to the intestine, liver, and kidney and reproductive system. Its molecular toxicology involves covalent binding to and inhibition of protein phosphatases, oxidative stress, cell death (autophagy, apoptosis, necrosis), and cytoskeleton disruption.
Microcystin-[D-Asp3]-LR/Microcystin A ([D-Asp3]-LR Microcystin) (1 μM) significantly increases Nrf2 activity, thus indicating oxidative stress response induction.
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