耗材描述
Uperolein
产品活性:Uperolein 是一种类似泡蛙肽的内十肽,由褐毛乌皮草 (Uperoleia rugosa) 和泥皮乌皮草 (Uperoleia marmorata) 产生。Uperolein 对胃肠道和纵向肌肉都有致痉挛的作用。
产品来源: https://www.medchemexpress.cn/uperolein.html
研究领域:Others
作用靶点:Others
In Vitro: Uperolein (10-100 ng/mL) is a tachykinin analogue, causes or reinforces rhythmic movements and increases the tone in isolated circular and longitudinal muscle of the human gastrointestinal tract from the stomach to the colon.
In Vivo: Uperolein (0.1 μg/kg and 5 μg/kg; i.v.; single dose) exhibits stimulation activity on the stomach of the anesthetized rat, displays a noticeable spasmogenic activity on the whole stomach from the fundus to the pylorus.
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