Calcitonin Gene Related Peptide (CGRP) II, rat 产品活性：Calcitonin Gene Related Peptide (CGRP) II, rat，一种 CGRP 受体 (CGRP receptors) 激活剂，是一种有效且持久的血管扩张剂。Calcitonin Gene Related Peptide (CGRP) II, rat 可用于心血管疾病的研究。 产品来源： https://www.medchemexpress.cn/calcitonin-gene-related-peptide-cgrp-ii-rat.html 研究领域：GPCR/G Protein | Neuronal Signaling 作用靶点：CGRP Receptor In Vitro: Calcitonin Gene Related Peptide (CGRP) II, rat induces vasodilator effects in small-diameter pig left anterior descending (LAD) coronary arteries with an EC50 value of 0.56 nM. Calcitonin Gene Related Peptide (CGRP) II, rat relaxes the spontaneous tone in isolated internal anal sphincter (IAS) strips, with an EC50 value of 83 μM. Calcitonin Gene Related Peptide (CGRP) II, rat (rβCGRP) inhibits [125I]hαCGRP binding (IC50: 7 nM), and stimulates cAMP accumulation (EC50: 0.56 nM) in the cells co-expressing mRAMP1 (mouse receptor-activity-modifying-protein 1) and rCRLR (rat calcitonin receptor-like receptor). Calcitonin Gene Related Peptide (CGRP) II, rat (rat-βCGRP, 0.01-100 nM) induces endothelium-independent relaxations in the coronary arteries from male and female Sprague-Dawley rats, with an IC50 value of 2.8 nM approximately. In Vivo: Calcitonin Gene Related Peptide (CGRP) II, rat (rat-βCGRP, bolus injection, 0.3 μg/kg, at 10 min intervals) induces hypotension and vasodilatation in Male Sprague-Dawley rats. 相关产品：Olcegepant | α-CGRP (mouse, rat) (TFA) | α-CGRP(human) | Cagrilintide acetate | Calcitonin (salmon) | Adrenomedullin (AM) (22-52), human | Rat CGRP-(8-37) | β-CGRP, human TFA | BCTC | Calcitonin (human) | Ubrogepant | HCGRP-(8-37) | MK-3207 | Telcagepant | Atogepant | Erenumab | Fremanezumab | Galcanezumab | Adrenomedullin (1-50), rat | SUN B8155 | Eptinezumab | Adrenomedullin (16-31), human | Calcitonin Gene Related Peptide (CGRP) II, rat TFA | Vazegepant | Chrysin 6-C-glucoside 8-C-arabinoside | [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。