耗材描述
Gluten Exorphin C
产品活性:Gluten exorphin C 是一种源自谷朊粉的阿片肽。在 GPI 和 MVD 检测中,抑制 μ opioid 和 δ opioid 活性,IC50 值分别为 40 μM 和13.5 μM。
产品来源: https://www.medchemexpress.cn/Gluten_Exorphin_C.html
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Opioid Receptor
In Vitro: Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC50s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity.
相关产品:Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Neuronal Signaling Compound Library | Neurotransmitter Receptor Compound Library | Anti-Obesity Compound Library | Peptide Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | Loperamide hydrochloride | DAMGO | Matrine | Sinomenine hydrochloride | Aticaprant | [Leu5]-Enkephalin | Norbinaltorphimine dihydrochloride | Dynorphin A | JDTic dihydrochloride | Nociceptin | JTC-801 | Tyr-Gly-Gly-Phe-Met-OH | SNC80 | β-Endorphin, human | Difelikefalin | Naloxone hydrochloride | Bisacodyl | BMS-986122 | LY2940094 | Ro 64-6198 | Alvimopan dihydrate | Corydaline | N-Desmethylclozapine | CTAP TFA | Morphiceptin | Naltriben mesylate | SB-612111 hydrochloride | Dermorphin | DPDPE
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