CRF, bovine TFA 产品活性：CRF, bovine (TFA) 是一种有效的 CRF 受体激动剂，能够取代 [125I-Tyr]ovine CRF，Ki 值为 3.52 nM。 产品来源： https://www.medchemexpress.cn/crf-bovine-tfa.html 研究领域：GPCR/G Protein 作用靶点：CRFR In Vitro: CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM. CRF shows pEC50s of 11.16, 8.53 and 8.70 for human CRF1, human CRF2 and rat CRF2α. CRF is released from hypothalamic-pituitary-adrenal (HPA) axis induced by stress, and leads to production of glucocorticoids which down regulate immune responses. CRF also has proinflammatory effects. CRF affects brain microvessel endothelial cells (BMEC) structure or function, CRF (100 nM) significantly increases cAMP in BMEC. 相关产品：Bioactive Compound Library Plus | Peptide Library | Antalarmin hydrochloride | R121919 | Verucerfont | Antisauvagine-30 TFA | Cortagine | NBI-27914 | Urocortin III, mouse TFA | Urocortin, human | CP 376395 | DMP 696 | Pexacerfont | Stressin I TFA | Tildacerfont | α-Helical CRF(9-41) | Urocortin, rat | [DPro5] Corticotropin Releasing Factor, human, rat TFA | Emicerfont | NVS-CRF38 | Sauvagine TFA | Urotensin I | (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) | (Tyr0)-Urocortin, rat | a-Helical Corticotropin Releasing Factor (12-41) | a-Helical Corticotropin Releasing Factor (9-41) 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。