耗材描述
PAR-4 Agonist Peptide, amide
产品活性:PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) 是一种蛋白酶激活受体-4 (PAR-4) 激动剂,对 PAR-1 或 PAR-2 都没有作用,且其作用会被 PAR-4 拮抗剂阻断。
产品来源: https://www.medchemexpress.cn/PAR-4_Agonist_Peptide,_amide.html
研究领域:GPCR/G Protein
作用靶点:Protease Activated Receptor (PAR)
In Vivo: Compared with their BALB/cBy controls, SCID mice have a significantly greater abdominal response to colorectal distension (CRD) at the distension levels of 0.04 to 0.1 mL increasing the intensity of EMG response by 384% to 132%, respectively (P<0.01; P<0.01; P<0.01; P<0.001). PAR-4 activation effectively reverses this hypersensitivity (P<0.01, P<0.05; P<0.05; P<0.05) .
相关产品:Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | Peptide Library | Coagulation and Anti-coagulation Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Bioactive Compound Library Max | Vorapaxar | TRAP-6 | Trypsin | AZ3451 | SLIGRL-NH2 | PAR-4 Agonist Peptide, amide TFA | 2-Furoyl-LIGRLO-amide | SCH79797 | GB-88 | Protease-Activated Receptor-2, amide | BMS-986120 | GB-110 hydrochloride | AZ8838 | I-191 | AC-55541 | FSLLRY-NH2 TFA | Parmodulin 2 | ENMD-1068 hydrochloride | PZ-128 | TFLLR-NH2(TFA) | Atopaxar | PAR-2-IN-1 | Protease-Activated Receptor-4 | PAR-2 (1-6) (human) | tcY-NH2 TFA | VKGILS-NH2 | Protease-Activated Receptor-1, PAR-1 Agonist TFA
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