耗材描述
Epitalon
产品活性:Epitalon 是一种抗衰老剂和端粒酶激活剂。Epitalon 对小鼠自发性肿瘤的发展具有抑制作用,具有 geroprotective 作用,通过鼻内给药可增加神经元活性。Epitalon 可用于癌症,衰老和色素性视网膜炎。
产品来源: https://www.medchemexpress.cn/epithalon.html
研究领域:Cell Cycle/DNA Damage
作用靶点:Telomerase
In Vitro: Addition of Epithalon peptide in telomerase-negative human fetal fibroblast culture induced expression of the catalytical subunit, enzymatic activity of telomerase, and telomere elongation, which can be due to reactivation of telomerase gene in somatic cells and indicates the possibility of prolonging life span of a cell population and of the whole organism.
In Vivo: Epitalon increases the lifespan of mice and fruit flies and restores the circadian rhythms of melatonin and cortisol production in old rhesus monkeys. At the same time, Epitalon prolongs the functional integrity of the eye retina in Campbell rats with hereditary Retinitis Pigmentosa and improves the visual functions in patients with pigmental retinal degeneration.
相关产品:Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Anti-Cancer Compound Library | Clinical Compound Library | Anti-Aging Compound Library | Drug Repurposing Compound Library | Rare Diseases Drug Library | Peptide Library | Human Metabolite Library | Bioactive Compound Library Max | BIBR 1532 | Hypericin | TMPyP4 tosylate | Abacavir | Cycloastragenol | Ceramides Mixture | 360A iodide | RHPS4 | MST-312 | Epitalon TFA | BMVC | Telomerase-IN-3 | Telomerase-IN-1 | Telomerase-IN-2 | 7-Deaza-2′-deoxyguanosine 5′-triphosphate | L2H2-6OTD | L2H2-6OTD intermediate-2 | Telomerase-IN-6
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