Gap 26 产品活性：Gap 26 是一种连接蛋白 (connexin) 模拟肽，由连接蛋白 connexin 43 (gap junction 阻滞剂)第一个胞外环的第 63-75 残基组成，包含SHVR氨基酸基序。 产品来源： https://www.medchemexpress.cn/Gap_26.html 研究领域：Cytoskeleton 作用靶点：Gap Junction Protein In Vitro: Gap 26 (0.25 mg/mL, 30 min) reduces the wave size in the three cell lines (RBE4, SV-ARBEC and ECV304). Gap 26 (0.25 mg/mL, 30 min) completely abolishes the InsP3-triggered ATP response and reduced the ATP release to below the control level, indicating that the basal ATP release is also affected.? Gap 26 does indeed significantly inhibit our InsP3-triggered intercellular calcium waves, but it did not have any effect on dye coupling through junctional channels as evidenced by the FRAP experiments, despite the fact that connexin 43 was present in the cell lines used.? Gap 26 (100-300 μM) dose-dependently reduces the rhythmic responses of rabbit superior mesenteric arteries, with IC50 of 28.4 ± 3.4 μM. 相关产品：Bioactive Compound Library Plus | Peptide Library | Carbenoxolone disodium | Meclofenamic acid sodium | Gap 27 | Larazotide acetate | Rotigaptide | Gap19 TFA | Tonabersat | AT-1002 TFA | Danegaptide Hydrochloride | TAT-Gap19 | Gap 26 TFA | Peptide5 TFA | Meclofenamic acid sodium hydrate | Meclofenamic acid-13C6 | Meclofenamic acid-d4 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。