[Pyr1]-Apelin-13 产品活性：[Pyr1]-Apelin-13 是一种高效的，选择性的内源性 apelin 受体激动剂。 产品来源： https://www.medchemexpress.cn/-Pyr1-Apelin-13.html 研究领域：GPCR/G Protein 作用靶点：Apelin Receptor (APJ) In Vitro: [Pyr1]-apelin-13 encapsulation in lipoPEG particles (lipoPEG-PA13) results in sustained and extended drug release under physiological conditions. In Vivo: [Pyr1]-apelin-13 nanocarriers in a mouse model of pressure-overload induced heart failure demonstrate a sustainable long-term effect of [Pyr1]-apelin-13 in preventing cardiac dysfunction. [Pyr1] apelin-13 (1, 5 μg) improves locomotor activity and reduces pain symptoms, cavity size and caspase-3 levels in rats. [Pyr1] apelin-13 (1, 5 μg) significantly increases thermal paw withdrawal latency. [Pyr1] apelin-13 in 5 μg dose also produces significant attenuation in paw withdrawal threshold compared to SCI animals from the second week post SCI. 相关产品：Bioactive Compound Library Plus | Peptide Library | Apelin-13 TFA | ML221 | Azelaprag | ML339 | BMS-986224 | ELA-32(human) TFA | Elabela(19-32) | CMF019 | MM 07 | Apelin-12 | MM 54 | ALX 40-4C Trifluoroacetate | Apelin-17(human, bovine) | (Ala13)-Apelin-13 TFA | ELA-21 (human) | Apelin-36(human) | Apelin-36(rat, mouse) | ELA-11(human) | ML233 | AM-8123 | Apelin agonist 1 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。