Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 产品活性：Fmoc-Thr[GalNAc(Ac)3-α-D]-OH 是用于研究制备癌症疫苗的结构单元。 产品来源： https://www.medchemexpress.cn/Fmoc-Thr-GalNAc-Ac-3-alpha-D-OH.html 研究领域：Others 作用靶点：Amino Acid Derivatives In Vitro: The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn +antigen). This precursor is generated in the Golgi apparatus on newly synthesized glycoproteins by a family of polypeptide α- N-acetylgalactosaminyltransferases (ppGalNAcTs) and then extended to the common core 1 O-glycan Galβ1-3GalNAcα1-OSer/Thr (T antigen) by a single enzyme termed the T-synthase (core 1 β3-galactosyltransferase or C1GalT). Formation of the active form of the T-synthase requires a unique molecular chaperone termed Cosmc, encoded by Cosmc on the X-chromosome. 相关产品：N6-Diazo-L-Fmoc-lysine | Fmoc-Arg(Pbf)-OH | L-tert-Leucine Methyl Ester Hydrochloride | (S)-2-Amino-6-((tert-butoxycarbonyl)amino)hexanoic acid | (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid | Fmoc-L-Lys(Dde)-OH | DL-Propargylglycine | Fmoc-Bip(4,4')-OH | Fmoc-Ala-OH | Fmoc-Gly-OH | Fmoc-Hyp(tBu)-OH | N-Boc-O-tosyl hydroxylamine | Fmoc-Ile-OH | N-ε-propargyloxycarbonyl-L-lysine hydrochloride | tert-Butyl 2-aminoacetate | Fmoc-Lys(Alloc)-OH | Fmoc-Pra-OH | Fmoc-Glu(OAll)-OH | Fmoc-L-Lys (Boc)-OH | Methyl (R)-2-((tert-butoxycarbonyl)amino)-3-iodopropanoate | N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester | (S)-2-amino-3-(4-benzoylphenyl)propanoic acid | Fmoc-Gly(allyl)-OH | Fmoc-Asp(OtBu)-OH | 2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride | Fmoc-D-Gln(Trt)-OH | Fmoc-Phe-OH | H-Lys(Fmoc)-OH | H-Lys(Z)-OtBu.HCl | N-Boc-L-tert-Leucine 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。