LXW7 产品活性：LXW7 是一种含 Arg-Gly-Asp (RGD) 的环状肽，是一种整合素 αvβ3 抑制剂，对 αvβ3 整联蛋白具有很高的结合亲和力，IC50 为 0.68 μM。LXW7 可增强 VEGFR-2 磷酸化和 ERK1/2 活化。具有抗炎活性。 产品来源： https://www.medchemexpress.cn/lxw7.html 研究领域：Cytoskeleton 作用靶点：Integrin In Vitro: LXW7 specially binds to αvβ3 integrin (Kd=76±10 nM). LXW7 binds strongly to αvβ3-K562 cells, weakly to αvβ5-K562 cells and αIIbβ3-K562 cells, and no binding to K562 cells. LXW7 has great potential as a highly efficient peptide ligand for targeted imaging and drug delivery. LXW7 acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. In Vivo: LXW7 (100 μg/kg; intravenous injection) significantly lowers infarct volumes and brain water content (BWC) LXW7-treated rats. The LXW7 treatment lowers the expression of pro-inflammatory cytokines. 相关产品：Cilengitide | Cyclo(-RGDfK) | Cucurbitacin B | GLPG0187 | E7820 | MK-0429 | CWHM-12 | Pyrintegrin | Lifitegrast | ATN-161 trifluoroacetate salt | Bexotegrast | Arg-Gly-Asp-Ser | Fibronectin | αvβ1 integrin-IN-1 TFA | Tirofiban | A-205804 | iRGD peptide | GPRP acetate | Carotegrast methyl | Eptifibatide | Vedolizumab | RGD peptide (GRGDNP) (TFA) | RGD | Natalizumab | Tetrac | Leukadherin-1 | BIO5192 | Cyclo(RGDyK) trifluoroacetate 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。