耗材描述
Tyr-Gly-Gly-Phe-Met-OH
产品活性:Tyr-Gly-Gly-Phe-Met-OH 通过结合阿片样物质受体 (opioid receptor),可调控人类免疫功能,抑制肿瘤生长。
产品来源: https://www.medchemexpress.cn/Tyr-Gly-Gly-Phe-Met-OH.html
研究领域:GPCR/G Protein | Neuronal Signaling
作用靶点:Opioid Receptor
In Vitro: Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems.
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