Protirelin acetate 产品活性：Protirelin Acetate 是一种高度保守的神经肽，发挥促甲状腺激素 (TSH) 水平的激素控制作用，及神经调节功能。 产品来源： https://www.medchemexpress.cn/Protirelin-Acetate.html 研究领域：Vitamin D Related/Nuclear Receptor 作用靶点：Thyroid Hormone Receptor In Vivo: Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in the control of postembryonic growth and reproduction. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin. 相关产品：Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | FDA-Approved Drug Library | Drug Repurposing Compound Library | Endocrinology Compound Library | Anti-COVID-19 Compound Library | NMPA-Approved Drug Library | FDA Approved & Pharmacopeial Drug Library | Drug-Induced Liver Injury (DILI) Compound Library | Rare Diseases Drug Library | Peptide Library | Human Metabolite Library | Nuclear Receptor Compound Library | Osteogenesis Compound Library | Off-patent Drug Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Bioactive Compound Library Max | Liothyronine | Resmetirom | L-Thyroxine | Sobetirome | PCO371 | Abaloparatide TFA | NH-3 | Taltirelin | Tiratricol | TR antagonist 1 | (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) | 3,5-Diiodothyropropionic acid | Reverse T3 | AH3960 | Parathyroid Hormone (1-34), bovine | Protirelin | Debutyldronedarone hydrochloride | Eprotirome | CO23 | MB-07811 | Parathyroid hormone (1-34) (rat) acetate | TI17 | DS69910557 | (Glu2)-TRH 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。