耗材描述
Thonningianin B
产品活性:Thonningianin B 是一种抗氧化剂和自噬 (autophagy) 增强剂。
产品来源: https://www.medchemexpress.cn/thonningianin-b.html
研究领域:Autophagy
作用靶点:Autophagy
来源:植物 | 蛇菰科 | 莲花菰
结构分类:酚类 | 多酚类 | 结构分类
In Vitro: Thonningianin B shows strong scavenging action against the DPPH radical. The DPPH radical is scavenged completely by a 34.5 µM solution of Thonningianin B. In a separate experiment, an IC50 value of Thonningianin B is determined to be 21 μM.
Thonningianin B (0-100 μM; 24 h) inhibits BV-2 cell viability with an IC50 of 46.74 μM.
Thonningianin B (10 μM; 24 h) significantly improves the ratio of LC3-II/LC3-I and the average number of GFP-LC3 puncta per cell in BV-2 cells.
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