Mycalolide B 产品活性：Mycalolide-B 是一种海绵肌动球蛋白 ATPase 特异性抑制剂。在 Ca2+ 存在时，Mycalolide-B 抑制 ATP 诱导的收缩和 Mg2+-ATPase 活性。 产品来源： https://www.medchemexpress.cn/mycalolide-b.html 研究领域：Anti-infection 作用靶点：Antibiotic 结构分类：生物碱 | 其他类生物碱 | 结构分类 In Vitro: Mycalolide-B belongs to macrolide antibiotics and consists of tris-oxazole with strong cytotoxic activity (IC50: 10-50 nM for growth of L1210 murine leukemia cells). Mycalolide-B, a toxin isolated from marine sponge, inhibits smooth muscle contractions without changing cytosolic Ca2+ levels. Mycalolide-B also inhibits Ca2+-induced contraction in permeabilized smooth muscles. Mycalolide-B inhibits superprecipitation and Mg2+-ATPase activity stimulated by Ca2+ without changing myosin light chain phosphorylation. Mycalolide-B inhibits ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+. 相关产品：Rapamycin | Cycloheximide | Chloroquine | Doxorubicin hydrochloride | Bafilomycin A1 | Dexamethasone | Puromycin dihydrochloride | Staurosporine | Actinomycin D | Etoposide | G-418 disulfate | Nigericin sodium salt | Cyclosporin A | 5-Azacytidine | Brefeldin A | Bleomycin sulfate | Ionomycin | Hygromycin B | Mitomycin C | Resveratrol | Tunicamycin | Doxycycline hyclate | Tacrolimus | Oligomycin | Streptozotocin | Neomycin sulfate | Wortmannin | Camptothecin 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。