耗材描述
Plantanone B
产品活性:Plantanone B 是一种中等抗氧化剂,IC50 为 169.8±5.2 μM。Plantanone B 具有显著的绵羊 COX-1 抑制活性和中等的 COX-2 抑制活性。Plantanone B 有研究炎症相关疾病的潜力。
产品来源: https://www.medchemexpress.cn/plantanone-b.html
研究领域:Immunology/Inflammation
作用靶点:COX
来源:植物 | 山茶科 | 油茶
结构分类:黄酮类 | 黄酮醇 | 酚类 | 多酚类
In Vitro: The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM.Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively..Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively.
相关产品:Acetaminophen | Indomethacin | EIPA | Celecoxib | Aspirin | Oxidopamine hydrobromide | Deferiprone | Diclofenac | Gallic acid | Ibuprofen | Catechin | 20(S)-Ginsenoside Rg3 | Cucurbitacin B | Meloxicam | Carprofen | Naproxen | (-)-Epicatechin | NS-398 | Xanthohumol | Flufenamic acid | Salicylic acid | Phenacetin | Hederagenin | Rebamipide | SC-560 | Ketoprofen
品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物,我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物;10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域;设有专业的实验中心和严格的质控、验证体系;提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;产品的生物活性多经各国客户实验验证;Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;与世界各大制药公司及知名科研机构建立了长期的合作。