Angoline 产品活性：Angoline 是一种有效的、选择性的 IL6/STAT3 信号通路抑制剂，IC50 为 11.56 μM。Angoline 抑制 STAT3 磷酸化及其靶基因表达，并抑制癌细胞增殖。 产品来源： https://www.medchemexpress.cn/angoline.html 研究领域：JAK/STAT Signaling | Stem Cell/Wnt 作用靶点：STAT 来源：植物 | 罂粟科 | 博落回 结构分类：生物碱 | 异喹啉类生物碱 | 结构分类 In Vitro: Angoline (0-100 μM; 1 h) inhibits STAT3, STAT1 and NF-κB signaling pathways with IC50 values of 11.56, ＞100 and ＞100 μM, respectively.? Angoline (0-100 μM; 2 h) affects phosphorylation of STAT3.? Angoline (0-100 μM; 72 h) inhibits MDA-MB-231, H4 and HepG2 cells proliferation. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | JAK/STAT Compound Library | Kinase Inhibitor Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Differentiation Inducing Compound Library | Alkaloids Library | Anti-Breast Cancer Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Anti-Obesity Compound Library | Transcription Factor-Targeted Library | Anti-Cancer Natural Product Library | Plant-Sourced Natural Product Library | Cancer Stem Cells Compound Library | Highly Selective Inhibitors Library | Anti-Hematopathy Compound Library | Bioactive Compound Library Max | Stattic | Fludarabine | AG490 | Cilengitide | Homoharringtonine | Niclosamide | AS1517499 | C188-9 | Artesunate | TPCA-1 | Colivelin TFA | Napabucasin | WP1066 | NSC 74859 | STAT5-IN-1 | Butyzamide | Cryptotanshinone | Astaxanthin | Scutellarin | Pimozide | RO8191 | AC-4-130 | SD-36 | Glycodeoxycholic Acid | Saikosaponin D | Cucurbitacin I | Diosgenin | 2-NP | BP-1-102 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。