Millepachine 产品活性：Millepachine 是来自中草药 Millettia pachycarpa Benth 的生物活性天然查尔酮，在体内外对多种人类癌细胞均显示出强大的抗肿瘤作用。 产品来源： https://www.medchemexpress.cn/millepachine.html 研究领域：Apoptosis 作用靶点：Apoptosis 来源：植物 | 豆科 | 厚果崖豆藤 结构分类：黄酮类 | 查耳酮 In Vitro: Millepachine (1.25-20 μM; 48 h) remarkably inhibits the proliferation of cisplatin-resistant A2780CP cells. Millepachine (2-8 μM; 24 or 48 h) induces G2/M arrest and apoptosis cisplatin-sensitive A2780S and cisplatin-resistant A2780CP cells. Millepachine (2-8 μM; 24 h) decreases topoisomerase II levels in A2780S and A2780CP cells. Millepachine (2-8 μM; 24 h) inhibits ATP-binding cassette transporter activity in A2780CP cells. In Vivo: Millepachine (20 mg/kg; i.v. every two days for 14 day) inhibits tumor growth in mice. Millepachine (20 mg/kg; i.v. every two days for 14 day) does not induce acquired drug resistance in an excised A2780S xenograft model. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Natural Product Library | Anti-Cancer Compound Library | Flavonoids Library | Anti-Cancer Natural Product Library | Plant-Sourced Natural Product Library | Cell Death Library | Bioactive Compound Library Max | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Rotenone | Etoposide | Elesclomol | Ruxolitinib | Monomethyl auristatin E | DAPT 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。