耗材描述
Levomenol
产品活性:Levomenol ((-)-α-Bisabolol) 是一种单环倍半萜醇,具有抗氧化、抗炎和抗凋亡的作用。Levomenol 还具有神经保护作用,通过减少小鼠永久性局灶性脑缺血诱导的促炎标志物,防止神经元损伤和记忆缺陷。Levomenol 减轻三叉神经性疼痛啮齿动物模型的伤害性行为和中枢敏感性。
产品来源: https://www.medchemexpress.cn/levomenol.html
研究领域:Apoptosis
作用靶点:Apoptosis
来源:植物 | 其他科
结构分类:萜类 | 倍半萜 | 结构分类
In Vivo: Levomenol ((-)-α-Bisabolol) (100-200 mg/kg; p.o.; one day before and 1 h after pMCAO; once daily for the following five day; Male Swiss mice) significantly reduces the infarcted area and neurological deficits caused by pMCAO. pMCAO: permanent media cerebral artery occlusion.
(−)-α-bisabolol exerts anti-inflammatory effects by reducing astrogliosis, MPO activity, and TNF-α and iNOS production.
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