5,​7,​4'-​Trimethoxyflavone 产品活性：5,7,4’-Trimethoxyflavone 可从药用植物 Kaempferia parviflora (KP) 中分离出来。5,7,4’-Trimethoxyflavone 是 CFTR 激活剂，EC50为64 μM。5,7,4’-Trimethoxyflavone 诱导细胞凋亡，增加 caspase-3 的蛋白水解活化，聚 (ADP-核糖) 聚合酶 (PARP) 蛋白的降解。5,7,4’-Trimethoxyflavone 有抗肿瘤活性。5,7,4’-Trimethoxyflavone 可用于预防皮肤老化和氧化应激相关研究。 产品来源： https://www.medchemexpress.cn/5-7-4-trimethoxyflavone.html 研究领域：Apoptosis | Epigenetics | Cell Cycle/DNA Damage | Metabolic Enzyme/Protease | Membrane Transporter/Ion Channel 作用靶点：Apoptosis | Caspase | PARP | Endogenous Metabolite | CFTR 来源：植物 | 姜科 | 小花山柰 结构分类：黄酮类 | 黄酮 | 结构分类 In Vitro: 5,7,4’-Trimethoxyflavone (12.5, 25, 50, 100, 200 μM, 24, 48 h) inhibits cell proliferation in SUN-16 cells. 5,7,4’-Trimethoxyflavone (12.5, 25, 37.5, 50 μM, 24 h) induces apoptosis in SUN-16 cells through endoplasmic reticulum stress-regulated proteins. 5,7,4’-Trimethoxyflavone (6.25, 12.5 μM, 24 h) inhibits the activity of TNF-α induced ROS and pro-inflammatory regulators in HDFs cells.