Okanin 产品活性：Okanin 是 Coreopsis tinctoria 的有效成分。Okanin 通过抑制 TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。 产品来源： https://www.medchemexpress.cn/okanin.html 研究领域：Immunology/Inflammation | NF-κB 作用靶点：Toll-like Receptor (TLR) | NF-κB 来源：植物 | 豆科 | 紫荆 | 植物 | 菊科 结构分类：黄酮类 | 查耳酮 | 酚类 | 多酚类 In Vitro: Okanin significantly inhibits LPS-induced TLR4 expression in BV-2 cells. Okanin inhibits the translocation of the NF-κB p65 subunit from the cytosol to the nucleus. Okanin significantly suppresses LPS-induced iNOS expression and also inhibites IL-6 and TNF-α production and mRNA expression in LPS-stimulated BV-2 cells. 相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Immunology/Inflammation Compound Library | NF-κB Signaling Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Small Molecule Immuno-Oncology Compound Library | Anti-Aging Compound Library | Antioxidant Compound Library | Differentiation Inducing Compound Library | Lipid Compound Library | Oxygen Sensing Compound Library | Anti-Cardiovascular Disease Compound Library | Phenols Library | Pyroptosis Compound Library | Traditional Chinese Medicine Active Compound Library | Flavonoids Library | Anti-Breast Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Obesity Compound Library | Transcription Factor-Targeted Library | Anti-Liver Cancer Compound Library | Antidepressant Compound Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Anti-Prostate Cancer Compound Library | Cancer Stem Cells Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Autoimmune Disease Compound Library | Highly Selective Inhibitors Library | Anti-Hematopathy Compound Library | Anti-Ovarian Cancer Compound Library | Multi-Target Compound Library | Radioprotector Library | Bioactive Compound Library Max | Anti-Fibrosis Compound Library | Phorbol 12-myristate 13-acetate | Chloroquine | Lipopolysaccharides | Bortezomib | Resatorvid | BAY 11-7082 | Resiquimod | Polyinosinic-polycytidylic acid | TAK-243 | JSH-23 | Shikonin | Sulfasalazine | Triptolide | Aspirin | C29 | Imiquimod | Pyrrolidinedithiocarbamate ammonium | Hydroxychloroquine | Baicalin | Dihydroartemisinin | 5-Aminosalicylic Acid | Parthenolide | Pam3CSK4 TFA | CBL0137 hydrochloride | Isoginkgetin | BAY 11-7085 | Rocaglamide | Enpatoran 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。