耗材描述
Hypophyllanthin
产品活性:Hypophyllanthin 是 Phyllanthus spp 中主要的一种木质素,具有很强的抗炎活性。Hypophyllanthin 能直接抑制 P-gp 的活性,而不干扰 MRP2 活性。
产品来源: https://www.medchemexpress.cn/hypophyllanthin.html
研究领域:Membrane Transporter/Ion Channel
作用靶点:P-glycoprotein
来源:植物 | 大戟科 | 叶下珠
结构分类:苯丙素类 | 木脂素 | 结构分类
In Vitro: Hypophyllanthin down-regulates COX-2, TNF-α, and IL-1β gene expressions in U937 macrophages by interfering with the activation of NF-κB, MAPKs, and Akt.
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